Is ProPulse Acoustic Pulse Therapy For E.D. Safe for Men on Anticoagulants?

If you take anticoagulants for cardiovascular disease and you’re wondering if shockwave pulse therapy is safe – like ProPulse therapy for ED – then this piece of new research will likely interest you.

It has to do with cardiovascular disease and shockwave therapy for ED.

A recent clinical study published in the Journal of Sexual Medicine made an important observation when it comes to men who are on anticoagulants and receive low-intermittent shockwave therapy for erectile dysfunction.

Low intermittent shockwave is the underlying technology of ProPulse therapy for erectile dysfunction.

First, a few things that are important to understand when it comes to ED and anticoagulants.

Erectile Dysfunction Due to Poor Blood Flow

Over 70% of men with Erectile Dysfunction have the type that is caused by poor blood flow to the penis.

The condition is called vasculogenic ED.

In fact, men with cardiovascular disease and or diabetes have a greater risk of having problems with achieving erections that are strong enough for satisfying sex.

In other words, men with cardiovascular problems and diabetes are more likely to have erectile dysfunction.

Now, a significant percentage of men with both cardiovascular disease and erectile dysfunction take anticoagulants to “thin” the blood by reducing how well it normally clots, or to make existing clots smaller.


It helps to prevent blockages from blood clots that cause heart attack and stroke.

Here’s how it works.

One way to keep blood from clotting normally is to take medications that discourage platelets in the blood from clumping together.

platelets in blood surrounded by red blood cells

For example, Aspirin is one such drug. 

Platelets are the tiny microscopic bags of clotting molecules in blood.

And these drugs are grouped together into the antiplatelet category of anticoagulants.

Anticoagulants and Shockwave Therapy

So, a good question to ask is

for men taking anticoagulants, is shockwave therapy [ such as ProPulse ] for ED safe?

That’s exactly the question posed by a group of researchers studying erectile dysfunction and cardiovascular disease.

Let’s remember,

the technology underlying ProPulse therapy for ED goes by a variety of technical generic names:

  • ESWT (Extracorporeal ShockWave Therapy),
  • LiST (Low Intermittent Shockwave Therapy),
  • EPAT (Extracorporeal Pulse Activation Treatment)
  • APT (Acoustic Pulse Therapy).

There are a few others too like “acoustic wave therapy” and “shockwave therapy.”

What the Research Shows

This is the first study that reports the safety of LiST shockwave therapy on a group of men with cardiovascular disease who take anticoagulants.

The authors note that a limitation of their research is that “it is a pulled data analysis, based on 2 randomized studies, which did not have safety of LiST as a primary outcome.”

You can find the study’s abstract on PubMed here.

The Current Study By The Numbers


According to the study’s authors, shockwave therapy for ED “seems to be a safe and well-tolerated treatment option for vasculogenic ED in patients on antiplatelet medication.

So what do you think of the news when it comes to anticoagulants, cardiovascular disease and shockwave therapy like ProPulse?

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